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Article

Insights about minority HIV-1 strains in transmitted drug resistance mutation dynamics and disease progression.

The Journal of antimicrobial chemotherapy - 1 Jul 2018

Leda Ana Rachel, Hunter James, Oliveira Ursula Castro, Azevedo Inacio Junqueira, Sucupira Maria Cecilia Araripe, Diaz Ricardo Sobhie

Abstract excerpt

Objectives: The presence of minority transmitted drug resistance mutations was assessed using ultra-deep sequencing and correlated with disease progression among recently HIV-1-infected individuals from Brazil. Methods: Samples at baseline during recent infection and 1 year after the establishment of the infection were analysed. Viral RNA and proviral DNA from 25 individuals were subjected to ultra-deep...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29684141
DOI: 10.1093/jac/dky132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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