Article

Influence of MIF polymorphisms on CpG island hyper-methylation of CDKN2A in the patients with ulcerative colitis

2020-10-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> <italic>CDKN2A</italic> hypermethylation is among the major events associated with carcinogenesis and is also observed in non-neoplastic colonic mucosa in patients with ulcerative colitis (UC). Macrophage migration inhibitory factor (MIF) plays a crucial role in promoting gastrointestinal inflammation characteristic of UC. The aim of this study is to explore ass...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a00ac486-07df-5280-8dcd-20b58867dd49
DOI: 10.21203/rs.3.rs-57255/v4

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Influence of MIF polymorphisms on CpG island hyper-methylation of CDKN2A in the patients with ulcerative colitisDOI 10.21203/rs.3.rs-57255/v4Read

Influence of MIF polymorphisms on CpG island hyper-methylation of CDKN2A in the patients with ulcerative colitis.Semantic proximity Read

Host genetic factors, related to inflammatory response, influence the CpG island methylation status in colonic mucosa in ulcerative colitis.Semantic proximity Read

A systematic review of the role of DNA methylation on inflammatory genes in ulcerative colitis.Semantic proximity Read

Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: an association study in New Zealand Caucasians and meta-analysis.Semantic proximity Read

Effect of MDR1 gene promoter methylation in patients with ulcerative colitis.Semantic proximity Read

Macrophage migration inhibitory factor, Toll-like receptor 4, and CD14 polymorphisms with altered expression levels in patients with ulcerative colitis.Semantic proximity Read

Association Between Genetic Polymorphism of the MIF Gene and Colorectal Cancer in Taiwan.Semantic proximity Read

Effect of polymorphisms of IL-17A, -17F and MIF genes on CpG island hyper-methylation (CIHM) in the human gastric mucosa.Semantic proximity Read

Hypermethylation of ITGA4, TFPI2 and VIMENTIN promoters is increased in inflamed colon tissue: putative risk markers for colitis-associated cancerSemantic proximity Read

DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells.Semantic proximity Read

Evaluation of the TLR 4 and TLR 5 genes methylation and mRNA expression in patients with Inflammatory Bowel DiseaseSemantic proximity Read

Macrophage Migration Inhibitory Factor (MIF) Gene Promotor Polymorphism Is Associated with Increased Fibrosis in Biliary Atresia Patients, but Not with Disease Susceptibility.Semantic proximity Read