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Article

No association between common variants in glyoxalase 1 and autism spectrum disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2008

Rehnström Karola, Ylisaukko-Oja Tero, Vanhala Raija, von Wendt Lennart, Peltonen Leena, Hovatta Iiris

Abstract excerpt

The autism spectrum disorders (ASDs) are complex diseases with a strong genetic component. Numerous candidate gene studies have tested association between various functional and positional candidate genes and autism, but no common variation predisposing for autism has been identified to date. It has been previously proposed, that glyoxalase 1 (GLO1) might be involved in the pathogenesis of autism as GLO1 protein...

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Identifiers

PMID: 17722011
DOI: 10.1002/ajmg.b.30582

Genes

GLO1

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No association between common variants in glyoxalase 1 and autism spectrum disorders.PMID 17722011Read ↗

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Proteomic studies identified a single nucleotide polymorphism in glyoxalase I as autism susceptibility factor.Semantic proximity Read ↗

Weak association of glyoxalase 1 (GLO1) variants with autism spectrum disorder.Semantic proximity Read ↗

The GLO1 C332 (Ala111) allele confers autism vulnerability: family-based genetic association and functional correlates.Semantic proximity Read ↗

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