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Article

Association analysis of the functional Ala111Glu polymorphism of the glyoxalase I gene in panic disorder.

Neuroscience letters - 27 Mar 2006

Politi Pierluigi, Minoretti Piercarlo, Falcone Colomba, Martinelli Valentina, Emanuele Enzo

Abstract excerpt

The zinc metalloenzyme glyoxalase I (GLO1) is thought to play a role in anxiety disorders because a reduced brain expression of GLO1 has been associated with increased anxiety-behaviours in mice. Recently, a functional Ala111Glu polymorphism in GLO1 has been shown to result in a reduced enzyme activity. The present study tested the hypothesis that this common genetic variant could confer susceptibility to panic...

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Source

Identifiers

PMID: 16352396
DOI: 10.1016/j.neulet.2005.11.028

Genes

GLO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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