Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma

1 Jan 2011

Abstract excerpt

BACKGROUND: Adaptation to hypoxia and consequent pro-inflammatory gene expression of prostate and breast carcinomas have been implicated in the progression toward cancer malignant phenotype. Only partial data are available for the human tumor glioblastoma multiforme (GBM). The aim of our study was to analyze the hypoxic and pro-inflammatory microenvironment in GBMs and to demonstrate that in a stem/progenitor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers in Disease Mechanisms
Share to Glioma Diagnosis and Treatment
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21489226
DOI: 10.1186/1742-2094-8-32

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastomaPMID 21489226Read ↗

Integrated analysis identified core signal pathways and hypoxic characteristics of human glioblastomaSemantic proximity Read ↗

Human mesenchymal stem cells exploit the immune response mediating chemokines to impact the phenotype of glioblastoma.Semantic proximity Read ↗

Insights in the immunobiology of glioblastoma.Semantic proximity Read ↗

The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma.Semantic proximity Read ↗

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2αSemantic proximity Read ↗

Glioblastoma Microenvironment: From an Inviolable Defense to a Therapeutic ChanceSemantic proximity Read ↗

Gene Expression Profile of Glioblastoma Peritumoral Tissue: An Ex Vivo StudySemantic proximity Read ↗

Novel Function of Cancer Stem Cell Marker ALDH1A3 in Glioblastoma: Pro-Angiogenesis through Paracrine PAI-1 and IL-8Semantic proximity Read ↗

HIF-2α mediates a marked increase in migration and stemness characteristics in a subset of glioma cells under hypoxia by activating an Oct-4/Sox-2-Mena (INV) axisSemantic proximity Read ↗

A MT1-MMP/NF-κB signaling axis as a checkpoint controller of COX-2 expression in CD133(+) U87 glioblastoma cellsSemantic proximity Read ↗

Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy.Semantic proximity Read ↗

Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.