Article
Human mesenchymal stem cells exploit the immune response mediating chemokines to impact the phenotype of glioblastoma.
Cell transplantation - 1 Jan 2012
Motaln Helena, Gruden Kristina, Hren Matjaz, Schichor Christian, Primon Monika, Rotter Ana, Lah Tamara T
Abstract excerpt
In contrast to the application of human mesenchymal stem cells (hMSCs) in regenerative medicine, only a limited number of studies are addressing their use in anticancer therapy. As the latter may represent a new hope to improve the survival of patients with glioblastoma multiformae (GBM), the most common and malignant form of the brain tumors, we aimed to investigate the interactions of hMSCs and GBM cells under...
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