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Article

Next generation sequencing improves detection of drug resistance mutations in infants after PMTCT failure.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2015

Fisher Randall G, Smith Davey M, Murrell Ben, Slabbert Ruhan, Kirby Bronwyn M, Edson Clair, Cotton Mark F, Haubrich Richard H, Kosakovsky Pond Sergei L, Van Zyl Gert U

Abstract excerpt

BACKGROUND: Next generation sequencing (NGS) allows the detection of minor variant HIV drug resistance mutations (DRMs). However data from new NGS platforms after Prevention-of-Mother-to-Child-Transmission (PMTCT) regimen failure are limited. OBJECTIVE: To compare major and minor variant HIV DRMs with Illumina MiSeq and Life Technologies Ion Personal Genome Machine (PGM) in infants infected despite a PMTCT...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25542470
DOI: 10.1016/j.jcv.2014.11.014
PMCID: PMC4279108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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