Article
Induction therapy with protease-inhibitors modifies the effect of nevirapine resistance on virologic response to nevirapine-based HAART in children.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Feb 2011
Moorthy Anitha, Kuhn Louise, Coovadia Ashraf, Meyers Tammy, Strehlau Renate, Sherman Gayle, Tsai Wei-Yann, Chen Ya Hui, Abrams Elaine J, Persaud Deborah
Abstract excerpt
BACKGROUND: Nevirapine resistance after failed prophylaxis to prevent mother-to-child human immunodeficiency virus (HIV) transmission can compromise subsequent nevirapine-based highly active antiretroviral therapy (HAART). METHODS: Nevirapine-exposed children who achieved virologic suppression with lopinavir/ritonavir-based induction HAART before switch to nevirapine-based HAART or who continued the...
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