Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Body size, IGF and growth hormone polymorphisms, and colorectal adenomas and hyperplastic polyps.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Aug 2010

Wernli Karen J, Newcomb Polly A, Wang Yinghui, Makar Karen W, Shadman Mazyar, Chia Victoria M, Burnett-Hartman Andrea, Wurscher Michelle A, Zheng Yingye, Mandelson Margaret T

Abstract excerpt

OBJECTIVE: We examined the risk of colorectal polyps in relation to body size factors and candidate polymorphisms in selected genes of insulin-like growth factor (IGF1) (rs5742612), IGF1 receptor (IGF1R) (rs2229765), IGF binding protein 3 (IGFBP3) (rs2854746) and growth hormone (GH1) (rs2665802). DESIGN: Cases with colorectal adenomas (n=519), hyperplastic polyps (n=691), or both lesions (n=227), and controls...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Body Size
Share to Colon
Share to Colonic Polyps
Share to Colorectal Neoplasms
Share to Human Growth Hormone
Share to Hyperplasia
Share to Insulin-Like Growth Factor I

Source

Open in PubMed Open full text

Identifiers

PMID: 20580999
DOI: 10.1016/j.ghir.2010.04.001
PMCID: PMC2918710

Genes

IGF1
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Body size, IGF and growth hormone polymorphisms, and colorectal adenomas and hyperplastic polyps.PMID 20580999Read ↗

Genetic Obesity Variants and Risk of Conventional Adenomas and Serrated Polyps.Semantic proximity Read ↗

Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk.Semantic proximity Read ↗

Racial differences in the association of insulin-like growth factor pathway and colorectal adenoma risk.Semantic proximity Read ↗

Insulin-like growth factor polymorphisms and colorectal cancer risk.Semantic proximity Read ↗

Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk.Semantic proximity Read ↗

Leptin concentrations, leptin receptor polymorphisms, and colorectal adenoma risk.Semantic proximity Read ↗

Body size and risk of colorectal cancer molecular defined subtypes and pathways: Mendelian randomization analyses.Semantic proximity Read ↗

Genome-wide association study identifies possible genetic risk factors for colorectal adenomas.Semantic proximity Read ↗

Association of Body Mass Index With Colorectal Cancer Risk by Genome-Wide Variants.Semantic proximity Read ↗

Body mass index increases risk of colorectal adenomas in men with Lynch syndrome: the GEOLynch cohort study.Semantic proximity Read ↗

Variation in the association between colorectal cancer susceptibility loci and colorectal polyps by polyp type.Semantic proximity Read ↗

A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.