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Article

Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition.

Molecular psychiatry - 1 Jan 2012

Cahill M E, Jones K A, Rafalovich I, Xie Z, Barros C S, Müller U, Penzes P

Abstract excerpt

Neuregulin 1 (NRG1) is a secreted trophic factor that activates the postsynaptic erbB4 receptor tyrosine kinase. Both NRG1 and erbB4 have been repeatedly associated with schizophrenia, but their downstream targets are not well characterized. ErbB4 is highly abundant in interneurons, and NRG1-mediated erbB4 activation has been shown to modulate interneuron function, but the role for NRG1-erbB4 signaling in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21483438
DOI: 10.1038/mp.2011.35
PMCID: PMC3135693

Genes

NRG1
KALRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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