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Article

Inhibitory IgG receptor FcgammaRIIB fails to inhibit experimental autoimmune myasthenia gravis pathogenesis.

Journal of neuroimmunology - 1 Feb 2008

Li Jing, Tüzün Erdem, Wu Xiong Rong, Qi Hui Bin, Allman Windy, Saini Shamsher S, Christadoss Premkumar

Abstract excerpt

Deficiency of the inhibitory FcgammaRIIB renders mice susceptible to autoimmune disorders characterized with cellular infiltration of target tissue. To analyze the role of FcgammaRIIB in an antibody-mediated autoimmune disease, experimental autoimmune myasthenia gravis (EAMG), FcgammaRIIB knockout (KO) and wild-type mice were immunized with acetylcholine receptor (AChR). In contrast with previous reports,...

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Source

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PMID: 18207575
DOI: 10.1016/j.jneuroim.2007.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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