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Article

Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma.

Neoplasia (New York, N.Y.) - 1 Apr 2011

Wu I-Chen, Zhao Yang, Zhai Rihong, Liu Geoffrey, Ter-Minassian Monica, Asomaning Kofi, Su Li, Liu Chen-Yu, Chen Feng, Kulke Matthew H, Heist Rebecca S, Christiani David C

Abstract excerpt

There is an increasing incidence of esophageal adenocarcinoma (EA) among younger people in the western populations. However, the association between genetic polymorphisms and the age of EA onset is unclear. In this study, 1330 functional/tagging single-nucleotide polymorphisms (SNPs) from 354 cancer-related genes were genotyped in 335 white EA patients. Twenty important SNPs that have the highest importance...

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Source

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Identifiers

PMID: 21472143
DOI: 10.1593/neo.101722
PMCID: PMC3071087

Genes

BCL2
CASP8
NOS3
ABL1
GHRL
KDR
MMP14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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