P21 Ser31Arg and FGFR2 rs2981582 Polymorphisms as Risk Factors for Early Onset of Breast Cancer in Yogyakarta, Indonesia.

doi:10.31557/APJCP.2019.20.11.3305

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Article

P21 Ser31Arg and FGFR2 rs2981582 Polymorphisms as Risk Factors for Early Onset of Breast Cancer in Yogyakarta, Indonesia.

Asian Pacific journal of cancer prevention : APJCP - 1 Nov 2019

Purnomosari Dewajani, Raharjo Clarista, Kalim Alvin Santoso, Herviastuti Rahma, Yushan Markus, Fajar Rangga Athilah, Harris Karina Kazia, Wahyono Artanto

Abstract excerpt

OBJECTIVES: Breast cancer tend to be more progressive with poorer prognosis in younger patients than those at an older age. Single Nucleotide Polymorphisms (SNPs) of P53 Pro72Arg, MDM2 SNP309, P21 Ser31Arg, ER SNP594, HER2 Ile655Val, and FGFR2 rs2981582 have drawn attention as genetic factors associated with cancer risk. However, there were contradictory results involving different races and their association is...

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PMID: 31759353
DOI: 10.31557/APJCP.2019.20.11.3305
PMCID: PMC7063001

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