CASP8 -652 6N del and CASP8 IVS12-19G>A gene polymorphisms and susceptibility/prognosis of ESCC: a case control study in northern Indian population.

doi:10.1002/jso.21881

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Article

CASP8 -652 6N del and CASP8 IVS12-19G>A gene polymorphisms and susceptibility/prognosis of ESCC: a case control study in northern Indian population.

Journal of surgical oncology - 1 Jun 2011

Umar Meenakshi, Upadhyay Rohit, Kumar Shaleen, Ghoshal Uday Chand, Mittal Balraj

Abstract excerpt

BACKGROUND: Caspase8 influences carcinogenesis through regulation of apoptosis, hyperproliferation, and metastasis. Role of genetic variations in caspase8 has been explored in various cancers; however, their predictive and prognostic role in esophageal cancer is poorly understood. METHODS: We investigated the association of two potential caspase8 polymorphisms: CASP8 -652 6N del and CASP8 IVS12-19 G>A...

Topics

Carcinoma, Squamous Cell
Case-Control Studies
Caspase 8
Esophageal Neoplasms
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans
India

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphatic Metastasis

Male

Middle Aged

Polymorphism, Genetic

Prognosis

Sex Factors

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Open in PubMed

Identifiers

PMID: 21308686
DOI: 10.1002/jso.21881

Genes

CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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