Article
CASP8 -652 6N del and CASP8 IVS12-19G>A gene polymorphisms and susceptibility/prognosis of ESCC: a case control study in northern Indian population.
Journal of surgical oncology - 1 Jun 2011
Umar Meenakshi, Upadhyay Rohit, Kumar Shaleen, Ghoshal Uday Chand, Mittal Balraj
Abstract excerpt
BACKGROUND: Caspase8 influences carcinogenesis through regulation of apoptosis, hyperproliferation, and metastasis. Role of genetic variations in caspase8 has been explored in various cancers; however, their predictive and prognostic role in esophageal cancer is poorly understood. METHODS: We investigated the association of two potential caspase8 polymorphisms: CASP8 -652 6N del and CASP8 IVS12-19 G>A...
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