Article
Effect of neocortical and hippocampal amyloid deposition upon galaninergic and cholinergic neurites in AβPPswe/PS1ΔE9 mice.
Journal of Alzheimer's disease : JAD - 1 Jan 2011
Kelley Christy M, Perez Sylvia E, Overk Cassia R, Wynick David, Mufson Elliott J
Abstract excerpt
Amyloid-β (Aβ) plaques occur in close apposition to thickened or swollen cholinergic and galaninergic neurites within the neocortex and hippocampus in Alzheimer's disease (AD). Despite this observation, the effect of Aβ deposition upon cholinergic and galaninergic dystrophic neurite formation remains unclear. Therefore, the purpose of this study was to evaluate the interaction between Aβ deposition within the...
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