Article
An Update of Animal Models of Alzheimer Disease with a Reevaluation of Plaque Depositions
30 Jun 2013
Abstract excerpt
Animal models of Alzheimer disease (AD) are used to study the mechanisms underlying AD pathogenesis, genetic interactions with genes of interest, and environmental risk factors that cause sporadic AD as well as to test the therapeutic effects of AD drug-candidates on neuropathology and cognitive function. To attain a comparative view on the AD models developed, representative AD lines were selected and summarized...
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