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Article

Characterization of the effect of heat on agent strains of the transmissible spongiform encephalopathies.

The Journal of general virology - 1 Jul 2011

Somerville Robert A, Gentles Nicola

Abstract excerpt

The causal agents of the transmissible spongiform encephalopathy (TSE) diseases, sometimes called prion diseases, are characterized by high resistance to inactivation with heat. Results from thermal inactivation experiments on nine TSE strains, seven passaged in two PrP genotypes, showed differences in sensitivity to heat inactivation ranging over 17 °C. In addition, the rate of inactivation with increasing...

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Identifiers

PMID: 21471321
DOI: 10.1099/vir.0.030452-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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