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Article

The infectivity of transmissible spongiform encephalopathy agent at low doses: the importance of phospholipid.

Journal of applied microbiology - 1 Aug 2006

Gale P

Abstract excerpt

The issue of whether the mechanism of infection is independent or co-operative for low doses of transmissible spongiform encephalopathy (TSE) agent is critical for risk assessment. The susceptibility (and hence ID(50)) of individuals with the same prion protein (PrP) genotype may vary considerably with a small proportion being very susceptible. Assuming independent action, the incubation period (IP) would...

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Identifiers

PMID: 16882133
DOI: 10.1111/j.1365-2672.2006.03110.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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