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Article

Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy.

Journal of virology - 1 Jun 2000

Bartz J C, Bessen R A, McKenzie D, Marsh R F, Aiken J M

Abstract excerpt

Interspecies transmission of the transmissible spongiform encephalopathies (TSEs), or prion diseases, can result in the adaptation and selection of TSE strains with an expanded host range and increased virulence such as in the case of bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease. To investigate TSE strain adaptation, we serially passaged a biological clone of transmissible mink...

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Identifiers

PMID: 10823860
DOI: 10.1128/jvi.74.12.5542-5547.2000
PMCID: PMC112040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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