Article
Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation.
The Journal of clinical endocrinology and metabolism - 1 Feb 2005
Sorrentino Rosanna, Libertini Silvana, Pallante Pier Lorenzo, Troncone Giancarlo, Palombini Lucio, Bavetsias Vassilios, Spalletti-Cernia Daniela, Laccetti Paolo, Linardopoulos Spiros, Chieffi Paolo, Fusco Alfredo, Portella Giuseppe
Abstract excerpt
Alterations in chromosome number (aneuploidy) are common in human neoplasias. Loss of mitotic regulation is believed to induce aneuploidy in cancer cells and act as a driving force during the malignant progression. The serine/theronine protein kinases of aurora family genes play a critical role i...
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