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Article

Role of CLIC4 in the host innate responses to bacterial lipopolysaccharide.

European journal of immunology - 1 May 2011

He Guoan, Ma Yao, Chou Szu-Yi, Li Huihong, Yang Chingwen, Chuang Jen-Zen, Sung Ching-Hwa, Ding Aihao

Abstract excerpt

Chloride intracellular channel (CLIC) 4 has diverse functions in membrane trafficking, apoptosis, angiogenesis and cell differentiation. CLIC4 is abundantly expressed in macrophages, but its role in innate immune functions is unclear. Here, we show that primary murine macrophages express increased amounts of CLIC4 after exposure to bacterial lipopolysaccharide (LPS). Endogenous CLIC4 level was significantly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21469130
DOI: 10.1002/eji.201041266
PMCID: PMC3099427

Genes

CLIC4
CCL5
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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