Article
The association analysis of hOGG1 genetic variants and gastric cancer risk in a Chinese population.
Oncotarget - 4 Oct 2016
Lu Jiafei, Yin Yongmei, Du Mulong, Ma Gaoxiang, Ge Yuqiu, Zhang Qiang, Chu Haiyan, Tong Na, Wang Meilin, Qiu Jinrong, Zhang Zhengdong
Abstract excerpt
Human 8-oxoguanine DNA glycosylase (hOGG1) is known to play an important role in the prevention of carcinogenesis, including gastric cancer (GC). We performed a case-control study to investigate whether single nucleotide polymorphisms (SNPs) of hOGG1 are associated with GC risk in a Chinese population. Two potential functional tagSNPs (rs159153 and rs1052133) and a previously reported risk SNP (rs125701) were...
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