Article
Risk-association of DNA methyltransferases polymorphisms with gastric cancer in the Southern Chinese population.
International journal of molecular sciences - 1 Jan 2012
Yang Xue-Xi, He Xuan-Qiu, Li Fen-Xia, Wu Ying-Song, Gao Yang, Li Ming
Abstract excerpt
DNA hypomethylation and/or hypermethylation are presumed to be early events in carcinogenesis, and one or more DNA methyltransferases (DNMTs) have been suggested to play roles in carcinogenesis of gastric cancer (GC). However, there have been no systematic studies regarding the association between DNMT gene polymorphisms and GC risk. Here, we examined the associations of 16 single nucleotide polymorphisms (SNPs)...
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