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Article

Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma.

Haematologica - 1 Jul 2011

Jacobs Gunnar, Hellmig Stephan, Huse Klaus, Titz Andrea, Franke Andre, Kwiatkowski Ruta, Ott Stephan, Kosmahl Markus, Fischbach Wolfgang, Lucius Ralph, Klapper Wolfram, Fölsch Ulrich R, Hampe Jochen, Schreiber Stefan, Rosenstiel Philip

Abstract excerpt

BACKGROUND: Primary gastric B-cell lymphomas arise from mucosa-associated lymphatic tissue (MALT) in patients with chronic Helicobacter pylori infection. We investigated whether germline variants in the CDH1 gene, coding for E-cadherin, genetically predispose patients to primary gastric B-cell lymphoma. DESIGN AND METHODS: Single marker analyses of the CDH1 gene were conducted in patients with primary gastric...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21459793
DOI: 10.3324/haematol.2010.033126
PMCID: PMC3128217

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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