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Article

Using CSF biomarkers to replicate genetic associations in Alzheimer's disease.

Neurobiology of aging - 1 Jul 2012

Schott Jonathan M

Abstract excerpt

Defining cases and controls on the basis of biomarkers rather than clinical diagnosis may reduce sample sizes required for genetic studies. The aim of this study was to assess whether characterizing case/control status on the basis of cerebrospinal fluid (CSF) profile would increase power to replicate known genetic associations for Alzheimer's disease (AD). Independent of clinical diagnosis, Alzheimer's Disease...

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Identifiers

PMID: 21459483
DOI: 10.1016/j.neurobiolaging.2011.02.008
PMCID: PMC3150628

Genes

MAF
APOE
PICALM
TOMM40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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