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Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers

6 Sept 2022

Abstract excerpt

Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer's disease (AD) more directly than clinical diagnosis. Initiated by the European Alzheimer & Dementia Biobank (EADB), the largest collaborative effort on genetics underlying CSF biomarkers was established, including 31 cohorts with a total of 13,116 individuals (discovery...

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Alzheimer's disease research and treatments
Dementia and Cognitive Impairment Research
Genetic Associations and Epidemiology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36066633
DOI: 10.1007/s00401-022-02454-z

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