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Article

The impact of contralateral mastectomy on mortality in BRCA1 and BRCA2 mutation carriers with breast cancer.

Breast cancer research and treatment - 1 Jul 2011

Narod Steven A

Abstract excerpt

Among women with breast cancer and a BRCA1 or BRCA2 mutation, the lifetime risk of breast cancer may be as high as 40%. Many physicians recommend prophylactic contralateral mastectomy, which is an effective measure of minimising the risk of contralateral cancer. The benefits of preventive contralateral mastectomy are apparent within 10 years, in terms of preventing cancer, but a much longer time period is...

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Source

Identifiers

PMID: 21455666
DOI: 10.1007/s10549-011-1479-1

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The impact of contralateral mastectomy on mortality in BRCA1 and BRCA2 mutation carriers with breast cancer.PMID 21455666Read ↗

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Contralateral mastectomy improves survival in women with BRCA1/2-associated breast cancer.Semantic proximity Read ↗

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Risk reduction of contralateral breast cancer and survival after contralateral prophylactic mastectomy in BRCA1 or BRCA2 mutation carriers.Semantic proximity Read ↗

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