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Article

Life expectancy gains from cancer prevention strategies for women with breast cancer and BRCA1 or BRCA2 mutations.

JAMA - 2 Feb 2000

Schrag D, Kuntz K M, Garber J E, Weeks J C

Abstract excerpt

CONTEXT: Women with BRCA1- or BRCA2-associated breast cancer are at increased risk for contralateral breast cancer and ovarian cancer and therefore may consider secondary cancer prevention strategies, such as prophylactic surgery and tamoxifen therapy. It is not proven to what extent these strategies reduce risk of second cancers in such patients. OBJECTIVE: To examine the effect of tamoxifen therapy, bilateral...

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Source

Identifiers

PMID: 10665701
DOI: 10.1001/jama.283.5.617

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Life expectancy gains from cancer prevention strategies for women with breast cancer and BRCA1 or BRCA2 mutations.PMID 10665701Read ↗

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Effect of prevention strategies on survival and quality-adjusted survival of women with BRCA1/2 mutations: an updated decision analysis.Semantic proximity Read ↗

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