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Article

Decoding Waldenström Macroglobulinemia Through Genomics, Epigenomics and Cellular Interactions.

International journal of molecular sciences - 7 Jun 2026

Růžičková Tereza, Kaščák Michal, Chyra Zuzana, Sandecká Viera, Kotašková Jana, Ševčíková Sabina

Abstract excerpt

Waldenström macroglobulinemia is a rare lymphoplasmacytic malignancy characterized by bone marrow infiltration and monoclonal immunoglobulin M production. Despite its indolent clinical course, the disease exhibits considerable biological complexity driven by recurrent genetic alterations, dysregulated signaling pathways, and a supportive bone marrow microenvironment. The identification of MYD88 and CXCR4...

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Topics

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Share to Epigenesis, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 42352898
DOI: 10.3390/ijms27125173
PMCID: PMC13299230

Genes

BCL2
CXCR4
MYD88

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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