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Article

Characterization of the bone phenotype and fracture repair in osteopetrotic incisors absent rats.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 May 2011

McDonald Michelle M, Morse Alyson, Peacock Lauren, Mikulec Kathy, Schindeler Aaron, Little David G

Abstract excerpt

Osteopetrotic patients possess a genetic condition that leads to a deficiency in osteoclast number or function. Patients have a high bone density and suffer from an increased risk of fracture. The lack of normal osteoclast activity has the potential to impede repair by complicating orthopedic fixation and/or by affecting the biology of fracture healing. The naturally occurring incisors absent (ia/ia) rat was...

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Identifiers

PMID: 21437952
DOI: 10.1002/jor.21293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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