Article
Mineral density and bone strength are dissociated in long bones of rat osteopetrotic mutations.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2000
Tuukkanen J, Koivukangas A, Jämsä T, Sundquist K, Mackay C A, Marks S C
Abstract excerpt
Bone mineral density (BMD) and mechanical strength generally show strong positive correlations. However, osteopetrosis is a metabolic bone disease with increased skeletal density radiographically and increased risk of fracture. We have evaluated mechanical strength and mineral density in three osteopetrotic mutations in the rat (incisors-absent [ia/ia], osteopetrosis [op/op], and toothless [tl/tl]) to test the...
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