Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Localization of the gene causing the osteopetrotic phenotype in the incisors absent (ia) rat on chromosome 10q32.1.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 2004

van Wesenbeeck Liesbeth, Odgren Paul R, Mackay Carole A, Van Hul Wim

Abstract excerpt

UNLABELLED: The incisors absent rat is an osteopetrotic animal model. Segregation analysis in 37 affected animals from an outcross enabled us to assign the disease causing gene to a 4.7-cM interval on rat chromosome 10q32.1. Further analysis of the genes mapped in this region will provide more insight into the underlying pathogenesis. INTRODUCTION: Many of the insights into the factors that regulate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Osteopetrosis

Share to Pedigree

Share to Phenotype

Source

Identifiers

PMID: 14969387
DOI: 10.1359/jbmr.2004.19.2.183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Localization of the gene causing the osteopetrotic phenotype in the incisors absent (ia) rat on chromosome 10q32.1.PMID 14969387Read ↗

Localization of the gene responsible for the op (osteopetrotic) defect in rats on chromosome 10.Semantic proximity Read ↗

Localization of the gene causing autosomal dominant osteopetrosis type I to chromosome 11q12-13.Semantic proximity Read ↗

Refined genomic localization of the genetic lesion in the osteopetrosis (op) rat and exclusion of three positional and functional candidate genes, Clcn7, Atp6v0c, and Slc9a3r2.Semantic proximity Read ↗

Autosomal Dominant Osteopetrosis Type II.Semantic proximity Read ↗

Characterization of the bone phenotype and fracture repair in osteopetrotic incisors absent rats.Semantic proximity Read ↗

Three recessive genes for congenital osteopetrosis in Norway rat.Semantic proximity Read ↗

Genetic study of osteopetrosis in the Norway rat.Semantic proximity Read ↗

The osteopetrotic mutation toothless ( tl ) is a loss-of-function frameshift mutation in the rat Csf1 gene: Evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossificationSemantic proximity Read ↗

Identification of TCIRG1 and CLCN7 gene mutations in a patient with autosomal recessive osteopetrosis.Semantic proximity Read ↗

A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots.Semantic proximity Read ↗

Human autosomal recessive osteopetrosis maps to 11q13, a position predicted by comparative mapping of the murine osteosclerosis (oc) mutation.Semantic proximity Read ↗

Lessons from osteopetrotic mutations in animals: impact on our current understanding of osteoclast biology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.