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Article

Three recessive genes for congenital osteopetrosis in Norway rat.

The Journal of heredity - 1 Jan 2000

Moutier R, Toyama K, Cotton W R, Gaines J F

Abstract excerpt

In the rat, the autosomal recessive toothless (t1) mutation exhibits an acute form of osteopetrosis. This gene is not an allele of either ia or op that causes respectively, a transitory and acute form of the disease. Comparative radiographic study of t1/t1 and op/op mutants reveals some differences in respect to the size and shape of long bones. In contrast to op/op mutants, homozygous t1/t1 animals failed to...

Topics

Alleles
Animals
Genes, Recessive
Genetic Complementation Test
Osteopetrosis
Rats
Rodent Diseases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 780413
DOI: 10.1093/oxfordjournals.jhered.a108705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-780413-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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