Lack of evidence for rickets in the osteopetrotic rat mutation, toothless.

doi:10.1002/jbmr.5650091119

Article

Lack of evidence for rickets in the osteopetrotic rat mutation, toothless.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 1994

Seifert M F

Abstract excerpt

A common, but paradoxic, feature among osteopetrotic human infants is the presence of rickets. This disorder of mineralization is manifested radiographically and histologically by increased growth plate cartilage and hypertrophic cell zone thickness and excess metaphyseal osteoid and biochemicall...

Topics

Animals
Disease Models, Animal
Femur
Growth Plate
Hypophosphatemia, Familial
Mutation
Osteopetrosis
Phenotype
Rats
Tibia
Tooth Loss

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