Article
Genetic associations with brain cortical thickness in multiple sclerosis.
Genes, brain, and behavior - 1 Feb 2015
Matsushita T, Madireddy L, Sprenger T, Khankhanian P, Magon S, Naegelin Y, Caverzasi E, Lindberg R L P, Kappos L, Hauser S L, Oksenberg J R, Henry R, Pelletier D, Baranzini S E
Abstract excerpt
Multiple sclerosis (MS) is characterized by temporal and spatial dissemination of demyelinating lesions in the central nervous system. Associated neurodegenerative changes contributing to disability have been recognized even at early disease stages. Recent studies show the importance of gray matter damage for the accrual of clinical disability rather than white matter where demyelination is easily visualized by...
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