Article
Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence.
Proceedings of the National Academy of Sciences of the United States of America - 7 Jun 2011
Reese Michael L, Zeiner Gusti M, Saeij Jeroen P J, Boothroyd John C, Boyle Jon P
Abstract excerpt
Toxoplasma gondii, an obligate intracellular parasite of the phylum Apicomplexa, has the unusual ability to infect virtually any warm-blooded animal. It is an extraordinarily successful parasite, infecting an estimated 30% of humans worldwide. The outcome of Toxoplasma infection is highly dependent on allelic differences in the large number of effectors that the parasite secretes into the host cell. Here, we show...
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