PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3).

doi:10.1093/carcin/bgp307

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Article

PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3).

Carcinogenesis - 1 Mar 2010

Dossus Laure, Kaaks Rudolf, Canzian Federico, Albanes Demetrius, Berndt Sonja I, Boeing Heiner, Buring Julie, Chanock Stephen J, Clavel-Chapelon Francoise, Feigelson Heather Spencer, Gaziano John M, Giovannucci Edward, Gonzalez Carlos, Haiman Christopher A, Hallmans Göran, Hankinson Susan E, Hayes Richard B, Henderson Brian E, Hoover Robert N, Hunter David J, Khaw Kay-Tee, Kolonel Laurence N, Kraft Peter, Ma Jing, Le Marchand Loic, Lund Eiliv, Peeters Petra H M, Stampfer Meir, Stram Dan O, Thomas Gilles, Thun Michael J, Tjonneland Anne, Trichopoulos Dimitrios, Tumino Rosario, Riboli Elio, Virtamo Jarmo, Weinstein Stephanie J, Yeager Meredith, Ziegler Regina G, Cox David G

Abstract excerpt

Genes involved in the inflammation pathway have been associated with cancer risk. Genetic variants in the interleukin-6 (IL6) and prostaglandin-endoperoxide synthase-2 (PTGS2, encoding for the COX-2 enzyme) genes, in particular, have been related to several cancer types, including breast and pros...

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PMID: 19965896
DOI: 10.1093/carcin/bgp307
PMCID: PMC2832545

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PTGS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19965896-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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