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Article

The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis.

DNA repair - 5 May 2011

Abdulovic Amy L, Hile Suzanne E, Kunkel Thomas A, Eckert Kristin A

Abstract excerpt

Elucidating the sources of genetic variation within microsatellite alleles has important implications for understanding the etiology of human diseases. Mismatch repair is a well described pathway for the suppression of microsatellite instability. However, the cellular polymerases responsible for generating microsatellite errors have not been fully described. We address this gap in knowledge by measuring the...

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Identifiers

PMID: 21429821
DOI: 10.1016/j.dnarep.2011.02.003
PMCID: PMC3121764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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