Article
Catechol-O-Methyltransferase Gene Polymorphisms and the Risk of Chemotherapy-Induced Prospective Memory Impairment in Breast Cancer Patients with Varying Tumor Hormonal Receptor Expression.
Medical science monitor : international medical journal of experimental and clinical research - 28 Sept 2020
Li Wen, Zhao Jingjing, Ding Ke, Chao Herta H, Li Chiang-Shan R, Cheng Huaidong, Shen Li
Abstract excerpt
BACKGROUND Existing research evidence indicates that breast cancer patients have different degrees of cognitive dysfunction after chemotherapy, and polymorphisms in 3 genes (catechol-O-methyltransferase, COMT; apolipoprotein E, APOE; and brain-derived neurotrophic factor, BDNF) have been associated with cognitive impairment. However, the role of these 3 gene polymorphisms in modulating cognitive impairment in...
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