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Article

Amyloid precursor protein gene (APP) variation in late-onset Alzheimer's disease.

Journal of molecular neuroscience : MN - 1 Sept 2011

Miar Ana, Alvarez Victoria, Corao Ana I, Díaz Marta, Alonso Belén, Martínez Carmen, Calatayud María T, Menéndez Manuel, Morís Germán, Coto Eliecer

Abstract excerpt

Mutations in the beta-amyloid precursor protein gene (APP) have been found in familial early-onset Alzheímer's disease (AD). DNA variants at several genes have been linked to the risk of developing the most common late-onset form of AD (LOAD). A few studies analyzed the contribution of APP variants to LOAD, with negative or conflicting results. We determined the variation in the 18 APP exons and flanking intronic...

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Source

Identifiers

PMID: 21424791
DOI: 10.1007/s12031-011-9510-x

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Amyloid precursor protein gene (APP) variation in late-onset Alzheimer's disease.PMID 21424791Read ↗

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