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[Screening for mutations of the precursor of beta-amyloid protein in early forms of Alzheimer disease. French Study Group of Alzheimer Disease].

Revue neurologique - 1 Jan 1993

Abstract excerpt

Genetic linkage studies suggest that Alzheimer's disease (AD) is genetically heterogeneous and that in several early onset families the disease locus is close to the amyloid precursor protein (APP) gene on chromosome 21. Recently, several mutations of APP gene have been described. We screened 100 sporadic and familial cases of early onset AD in order to determine the frequency of two of these mutations, APP 717...

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Identifiers

PMID: 8023065

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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