Article
[The characteristics of the transformed phenotype and the expression of indicator plasmids in the cells of rat embryonic fibroblasts immortalized by oncogene E1Aad5 and transformed by oncogenes E1Aad5+c-Ha-ras].
Tsitologiia - 1 Jan 1990
Pospelova T V, Kisliakova T V, Medvedev A V, Svetlikova S B, Pospelov V A
Abstract excerpt
Rat embryonal fibroblasts of the second passage have been immortalized or transformed with the E1A region of the human adenovirus type 5 and the cloned c-Ha-ras oncogene. Several cell lines obtained greatly differ according to the criteria of the transformed phenotype: saturation cell density, th...
Topics
- Animals
- Cell Line
- Cell Transformation, Neoplastic
- Cell Transformation, Viral
- Cells, Cultured
- Embryo, Mammalian
- Fibroblasts
- Gene Expression
- Genes, ras
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Oncogene Proteins
- Oncogenes
- Phenotype
- Plasmids
- Rats
- Rats, Inbred Strains