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Article

A randomized controlled trial of genotype-based Coumadin initiation.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jun 2011

Burmester James K, Berg Richard L, Yale Steven H, Rottscheit Carla M, Glurich Ingrid E, Schmelzer John R, Caldwell Michael D

Abstract excerpt

PURPOSE: A randomized controlled trial was conducted in patients initiating warfarin to determine whether algorithms that incorporate genotypes affecting warfarin metabolism and function, and Vitamin K metabolism improve prediction of therapeutic warfarin dose and anticoagulation management. METHODS: A total of 230 patients were randomized to either a clinical arm where dosing algorithms considered only clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21423021
DOI: 10.1097/GIM.0b013e31820ad77d

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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