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Article

A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data.

Clinical medicine & research - 1 Aug 2005

Hillman Michael A, Wilke Russell A, Yale Steven H, Vidaillet Humberto J, Caldwell Michael D, Glurich Ingrid, Berg Richard L, Schmelzer John, Burmester James K

Abstract excerpt

BACKGROUND: Rapid genetic screening for cytochrome P450 (CYP) 2C9 variants may play a role in improving the efficacy and safety of warfarin in individuals with CYP2C9 variants. The feasibility of prospective CYP2C9 model-based warfarin dosing has not yet been assessed. OBJECTIVES: To evaluate the feasibility of applying a CYP2C9 gene-based warfarin dosing model in clinical practice. DESIGN: Prospective,...

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Source

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Identifiers

PMID: 16160068
DOI: 10.3121/cmr.3.3.137
PMCID: PMC1237155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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