Article
RNA structures, genomic organization and selection of recombinant HIV.
RNA biology - 1 Jan 2000
Simon-Loriere Etienne, Rossolillo Paola, Negroni Matteo
Abstract excerpt
Recombination is an evolutionary mechanism intrinsic to the evolution of many RNA viruses. In retroviruses and notably in the case of HIV, recombination is so frequent that it can be considered as part of its mode of replication. This process not only plays a central role in shaping HIV genetic diversity worldwide, but has also been involved in immune escape and development of resistance to antiviral treatments....
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