Article
DNA repair gene ERCC2 polymorphisms and risk of squamous cell carcinoma of the head and neck.
Experimental and molecular pathology - 1 Aug 2011
Gugatschka Markus, Dehchamani Dadbeh, Wascher Thomas C, Friedrich Gerhard, Renner Wilfried
Abstract excerpt
INTRODUCTION: Genetic aberrations of DNA repair enzymes are known to be common events and to be associated with different cancer entities. Aim of the following study was to analyze the genetic association of single nucleotide polymorphisms (SNP) of the DNA repair genes with the risk of squamous cell carcinoma of the head and neck (HNSCC). MATERIALS AND METHODS: Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2...
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