Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2) with predisposition to Squamous Cell Carcinomas of the Head and Neck (SCCHN) and Breast cancer in the north Indian population.

doi:10.1186/1756-9966-28-104

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Article

Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2) with predisposition to Squamous Cell Carcinomas of the Head and Neck (SCCHN) and Breast cancer in the north Indian population.

Journal of experimental & clinical cancer research : CR - 18 Jul 2009

Mitra Amit Kumar, Singh Neetu, Garg Vivek Kumar, Chaturvedi Rashmi, Sharma Mandira, Rath Srikanta Kumar

Abstract excerpt

BACKGROUND: Non-synonymous single nucleotide polymorphisms (SNPs) within vital DNA repair genes may cause reduction of activity leaving the genome unrepaired resulting in genomic instability and cancer. MATERIALS AND METHODS: The present endeavour involved study on the association of the SNP rs13181 (Lys751Gln/A18911C) in the Nucleotide Excision Repair (NER) pathway gene ERCC2 (excision repair cross-complementing...

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Identifiers

PMID: 19615095
DOI: 10.1186/1756-9966-28-104
PMCID: PMC2724389

Genes

ERCC2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2) with predisposition to Squamous Cell Carcinomas of the Head and Neck (SCCHN) and Breast cancer in the north Indian population.PMID 19615095Read ↗

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