Article
DNA repair gene polymorphisms and risk of head and neck cancer in the Tunisian population.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Mar 2014
Khlifi Rim, Kallel Imen, Hammami Bouthaina, Hamza-Chaffai Amel, Rebai Ahmed
Abstract excerpt
Altered activity of DNA repair enzymes may be involved in modulating cancer susceptibility and pathogenesis of head and neck cancer (HNC). We conducted a case-control study to test the association between three common single-nucleotide polymorphisms of XRCC1, ERCC2, and ERCC3 genes with HNC risk in Tunisian patients. To the best of our knowle dge, this is the first report on polymorphisms in XRCC1, ERCC2, and...
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