The Escherichia coli K-12 metJ193 allele contains a point mutation which alters the hydrophobic pocket responsible for in vitro binding of S-adenosylmethionine: effects on cell growth and induction of met regulon expression.

doi:10.1128/jb.172.7.3918-3924.1990

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The Escherichia coli K-12 metJ193 allele contains a point mutation which alters the hydrophobic pocket responsible for in vitro binding of S-adenosylmethionine: effects on cell growth and induction of met regulon expression.

Journal of bacteriology - 1 Jul 1990

Collier C D, Johnson J R

Abstract excerpt

The metJ193 allele encodes one of two identified temperature-sensitive Escherichia coli K-12 met repressors. The nucleotide sequence of the metJ193 allele was determined. The point mutation was a T to A transversion at base 170 of the metJ193 open reading frame and resulted in the substitution of...

Topics

Alleles
Amino Acid Sequence
Bacterial Proteins
Bacteriophage lambda
Base Sequence
Carbon-Oxygen Lyases
Enzyme Induction
Escherichia coli
Escherichia coli Proteins
Gene Expression Regulation, Bacterial
Genes, Regulator
Genotype
Glutamine
Kinetics

Source

Open in PubMed Open full text

Identifiers

PMID: 2141834
DOI: 10.1128/jb.172.7.3918-3924.1990
PMCID: PMC213374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2141834-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leucine

Lyases

Molecular Sequence Data

Mutation