Novel Escherichia coli K-12 mutants impaired in S-adenosylmethionine synthesis.

doi:10.1128/jb.172.8.4489-4496.1990

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Article

Novel Escherichia coli K-12 mutants impaired in S-adenosylmethionine synthesis.

Journal of bacteriology - 1 Aug 1990

Satishchandran C, Taylor J C, Markham G D

Abstract excerpt

S-Adenosylmethionine (AdoMet) plays a myriad of roles in cellular metabolism. One of the many roles of AdoMet in Escherichia coli and Salmonella typhimurium is as a corepressor of genes encoding enzymes of methionine biosynthesis. To investigate the metabolic effects of large reductions in intrac...

Topics

Chromosomes, Bacterial
DNA, Recombinant
Escherichia coli
Genotype
Immunoblotting
Immunodiffusion
Methionine Adenosyltransferase
Molecular Weight
Mutation
Plasmids
Restriction Mapping
S-Adenosylmethionine
Temperature
Transferases

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